Binge drinking
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Binge drinking | Binge drinking (consuming rapidly four or more alcoholic drinks over a short period of time) has been found to have a particularly negative impact on health (Roerecke et al 2014, Chen et al 2011). This pattern of consumption results in a rapid and relatively sustained increase in the alcohol concentration circulating throughout the body and brain (Wechsler et al 1998). Such a high blood alcohol concentration (BAC) can impact on metabolic processes in response to alcohol drinking such as the development of free radicals implicated in certain cancers (Brooks et al 2017). In these circumstances, the elimination of alcohol from the body via the enzymes ADH and ALDH may not be sufficiently effective (Seitz et al 2007) and a high BAC continues to circulate until it triggers the MEOS system to switch on, thereby increasing the capacity of the liver to eliminate the alcohol from the body. Thus, there is no doubt that binge drinkers have a high risk to develop cancer.
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