06 May 2014 In Cardiovascular System

BACKGROUND: Current alcohol intake has been associated with cardiovascular morbidity and mortality. The effect of past and lifetime drinking has received less attention. In the present study, the impact of current, past and lifetime drinking on cardiovascular events and all-cause mortality has been assessed. Secondly, the effect of accounting for covariates within these relationships has been studied. METHODS: The Lifestyle and Health study is a prospective cohort study in 2 regions of the Netherlands. Men and women aged 45 to 70 years registered in 34 general practices were followed over the period July 1996 to June 2001. At baseline, an extensive questionnaire had to be filled in. It included 3 questionnaires about alcohol intake: a Weekly Recall, a Quantity-Frequency about last year, and the Lifetime Drinking History questionnaire. Health problems were registered by the general practitioners. RESULTS: During follow-up, 679 men and 397 women had a cardiovascular event and 330 men and 204 women died. Current drinking was associated with lower risks of cardiovascular events (women) and all-cause mortality (men and women) compared with never drinkers. The relationships were strongest for alcohol intake measured with the Weekly Recall. Lifetime alcohol intake and alcohol intake in the distant past did not seem to be related to all-cause mortality or cardiovascular events. Adjustments for covariates weakened the relationships. CONCLUSIONS: Potential positive effects of drinking seem to be of a transient nature, as lifetime drinking and drinking in the past could not be related to all-cause mortality or cardiovascular events. The alleged benefits of current drinking at baseline diminished with increasing methodological quality and rigor.

06 May 2014 In Cancer




Epidemiologic findings are inconsistent concerning the association of endometrial cancer risk with alcohol consumption. Therefore, we conduct a meta-analysis of studies that assessed the association of alcohol consumption and the risk of endometrial cancer. A systematic literature search up to April 2010 was performed in MEDLINE and EMBASE, and study-specific risk estimates were pooled using a random-effects model. In the present study, six prospective and 14 case-control studies were included. Alcohol intake was not significantly associated with the risk of endometrial cancer among prospective studies (relative risk (RR): 1.04; 95% confidence interval (CI): 0.91-1.18) or among case-control studies (odds ratio (OR): 0.89; 95% CI: 0.76-1.05). However evidence from the results of our stratified analyses revealed that increased risk of endometrial cancer was associated with liquor consumption (RR: 1.22; 95% CI: 1.03-1.45) but null association with wine and beer consumption. In conclusion, alcohol consumption is not associated with the risk of endometrial cancer. Future studies should also examine whether the relation varies according to different type of alcoholic beverages.




13 February 2014 In Events
Protection and advancement of citizens’ health is a declared priority for the EU. Both prevention and medical treatment can contribute to health, but prevention has certain advantages. Among preventive actions, two are universal in their applicability: good nutrition and physical activity, which are applicable across the life span. 
The Conference, therefore, will deal with issues such as nutrition and physical activity during childhood and old age, alike, childhood obesity, policies to tackle diet-related NCDS, public health issues with a focus on the underprivileged, and scientific considerations for the formulation of strategies within the EU. 
With nutrition and physical activity being relevant to the entire life span, including the sensitive childhood and old age years, effective approaches, as well as their applicability to the EU population and its vulnerable subgroups need to be considered. 
Prospects for the encouragement of dietary patterns, like the ecologically friendly Mediterranean diet and adaptation of physical activity integrated in the daily life at the total population level, as well as their facilitation with a view to substantial health effects in the context of the modern EU lifestyle will be discussed. 
For more information about the conference, please visit the Greek Presidency's website.
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