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In three large US prospective studies, higher intake of alcoholic beverages (≥15g/day) during early adulthood was related to a higher risk of colorectal cancer later in life compared to non-drinkers. This risk was independent of the level of smoking in early adulthood and intake of alcoholic beverages during midlife. These results suggest that early adulthood may be a potential period where there is an increased susceptibility to colorectal cancer. Hur J, Smith-Warner SA, Rimm EB, Willett WC, Wu K, Cao…
The results of this large-scale prospective study with over 80,000 Chinese participants and a follow-up time of 10 years showed that participants who reported consuming between 1g and 150 g of alcohol/week had a lower risk for cardiovascular disease (CVD), cancer and total mortality compared to heavy drinker and non-drinkers. The authors explain that this study in an Asian population supports prior observations of a J-shaped association between the consumption of alcoholic beverages and chronic diseases (CVD and cancer) and…
This double-blind placebo-controlled trial evaluated the benefits of low-dose resveratrol supplementation on various aspects of healthy ageing in post-menopausal women. Dementia and cardiovascular diseases are the leading causes of death in older women. Over 55 years old women have a greater risk of cardiovascular disease than their male counterparts or younger women. The rapid mid-life decline in circulating estrogen following menopause is partly responsible for these differences. Estrogen plays an important role for memory retention, metabolic regulation and bone health…
Two well-known scientists and a family physician1 published three extensive reviews confirming the latest scientific evidence of the J-curve and discussing the methodological challenges, including the Mendelian randomisation (MR) but also possible practical implications of these results at individual and public health level2-4 . The following is a short summary of the very detailed discussion in these three publications. The cardiovascular benefits of moderate drinking were observed already in the 1960’s, but the results were initially disputed by the scientific…
Commentary and analysis by Prof. Nicolai Worm (WIC chair). Headlines recently reported “One small drink a day raises risk of irregular heartbeat”. These reports were based on a study, which found that - even though a moderate amount of alcohol can protect against heart failure - drinking the equivalent of a small glass of wine or beer per day was linked to an increased risk of atrial fibrillation (AF). The researchers assessed the drinking habits and the heart health of…
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