General Health

Moderate wine drinkers have a lower risk to die from any cause (lower total  mortality risk) than those who abstain or drink heavily. This widely accepted association is known as the J-curve. This J-curve is attributable to the beneficial effect on cardiovascular health which compensates the negative effects of some cancers resulting in a lower risk to die from any possible cause. The relative risk of dying is lowest among light to moderate drinkers and increased among abstainers. However, the risk increases dramatically with each drink above moderation. Thus, while one or two glasses can be considered “good for your health”, drinking more than what guidelines suggest will not provide more benefits, only more harm.

 

If consumed in excess, alcoholic beverages increase the exposure to a wide range of risk factors whereby the risk rises with the amount of alcohol consumed. Thus, it is crucial to prevent abusive consumption. Alcohol abuse is associated with a range of long-term chronic diseases that reduce the quality of life. These include hypertension, cardiovascular problems, cirrhosis of the liver, alcohol dependence, various forms of cancer, alcohol-related brain damage and a range of other problems. Not only the amount of alcohol but also the drinking patterns are important. Findings from a meta analysis support results from other studies that binge drinking is detrimental to heart health. The authors concluded that it is best for drinkers to avoid binge drinking -- not only because of the possible heart effects, but also because of more immediate risks, like accidents and violence.

 

In addition to health issues resulting from excessive alcohol consumption, there are social consequences, both for the drinker and for others in the community. The consequences include harm to family members (including children), to friends and colleagues as well as to bystanders and strangers.

 

The above summary provides an overview of the topic, for more details and specific questions, please refer to the articles in the database.

 

 

BACKGROUND & AIMS: Biological age (BA) is the hypothetical underlying age of an organism and has been proposed as a more powerful predictor of health than chronological age (CA). The difference between BA and CA (Deltaage) reflects the rate of biological aging, with lower values indicating slowed-down aging. We sought to compare the relationship of four a priori-defined dietary patterns, including a traditional Mediterranean diet (MD) and three non-Mediterranean diets, with biological aging (Deltaage) among Italian adults. We also examined distinctive nutritional traits of these diets as potential mediators of such associations. METHODS: Cross-sectional analysis on a sub-cohort of 4510 subjects (aged >/=35 y; 52.0% women) from the Moli-sani Study (enrolment, 2005-2010). Food intake was recorded by a 188-item semi-quantitative…
OBJECTIVES: To test the efficacy of calorie labelling for alcoholic and non-alcoholic beverages on restaurant menus on noticing calorie information, calorie knowledge, and perceived and actual influence on hypothetical beverage orders. METHODS: Participants included upper-level university students of legal drinking age residing in Ontario, Canada (n = 283). Using a between-groups experiment, participants were randomized to view one of two menus: (1) No Calorie Information (control), and (2) Calorie Information adjacent to each beverage. Participants completed a hypothetical ordering task, and measures related to noticing calorie information, calorie knowledge, and actual and perceived influence of calorie information on beverages ordered were assessed. Linear, logistic, and multinomial logistic regression models were used to examine the four outcomes. RESULTS: The odds of…
BACKGROUND: Risk genes linked to the development of gout have been identified, and lifestyle factors are related to gout risk. It remains unclear whether healthy lifestyle factors can mitigate the genetic risk of gout. Therefore, we aimed to explore whether and to what extent a healthy lifestyle can mitigate the risk of gout related to genetic factors. METHODS: Within the UK Biobank, 416,481 gout-free participants (aged 37-74) were identified at baseline. Polygenic risk for gout was assessed and categorized as low (lowest tertile), middle (tertile 2), and high (highest tertile). Healthy lifestyle factors included no/moderate alcohol consumption, no smoking, physical activity, and a healthy diet. Participants were categorized into three groups according to their number of healthy lifestyle factors: unfavorable…
This work aimed to relate alcohol consumption with adherence to the Mediterranean diet (MD) and with food neophobia (FN) among Italian and Spanish university students. Volunteers (n = 194, 108 Italian and 86 Spanish), recruited at the La Sapienza University of Rome and the Catholic University of Murcia, filled in standardized questionnaires to evaluate alcohol consumption (AUDIT), FN (FN Scale: FNS), and adherence to the MD (MDS-14, MED-55, QueMD). In addition to the previously reported QueMD sub-score (aMED), a sub-score for non-typical MD foods (ntMED, carbonated and/or sugar-sweetened beverages (soft drinks), butter, margarine, or cooking cream, and manufactured sweets, pastries, and cakes) was evaluated. Italian females had higher MED-55 and FNS scores, and a lower AUDIT score than Spaniards (p…
BACKGROUND AND AIMS: Alcohol consumption is a major threat to global health. The aim of the present study was to explore the association between alcohol consumption and chronic kidney disease (CKD) in a Chinese population. METHODS AND RESULTS: A total of 4664 participants, aged >/=18 years, who participated in a baseline alcohol survey in 1997 and were followed up in 2009 of the China Health and Nutrition Survey (CHNS), were recruited in the current study. Data on alcohol consumption was obtained using standardized questionnaires, with CKD (defined as eGFR
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