Excess alcohol consumption is a leading contributor to the global burden of disease and a major risk factor for mortality. Yet, prior studies suggested that moderate alcohol consumption may be associated with a lower risk of cardiovascular disease (CVD) events. However, this evidence is based on data from younger individuals, and confirmation in older adults is lacking. Thus, we sought to investigate the risk of CVD events and all-cause mortality associated with alcohol consumption in initially healthy, older individuals.
For these post hoc analyses we used data from the ASPirin in Reducing Events in the Elderly (ASPREE) trial, which investigated the effect of low-dose...