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The J-shaped association between the risk of coronary artery disease and moderate drinking was confirmed by the current meta-analysis. Chinese researchers quantified the dose-response association between the consumption of alcoholic beverages and the risk of coronary artery disease (CAD) in a meta-analysis which included 18 prospective studies, with a total of 214 340 participants and 7756 CAD cases. The results showed a nonlinear J-shaped association between the intake of alcoholic beverages and the risk of CAD: compared to non-drinkers, the…
In an attempt to evaluate the immediate and long-term effects of alcohol intake, the current meta-analysis suggests that moderate drinking may be associated with an immediately higher risk of cardiovascular events, which disappears after 24 hours. While moderate intake of alcoholic beverages has long-term cardiovascular benefits, it is less clear, whether it could pose an acute increased cardiovascular risk. Researchers from the Harvard University in the US carried out a systematic review and meta-analysis of observational studies to examine the…
This study is the first study showing the relationship between the consumption of alcoholic beverages and the Cardio-Metabolic Index (CMI = an index indicating the risk of diabetes) and confirming the J-shaped association. Central obesity is an eminent risk factor for cardio-metabolic diseases. The widely applied Body Mass Index (BMI) is a simple index of weight-for-height that is commonly used to classify underweight, overweight and obesity in adults, but fails to distinguish weight from adiposity. It is central obesity, i.e.…
Two scientists, Richard M Hoffman (University of Hertfordshire, UK) and Mariette Gerber (French Food, Environment and Work Safety Agency, ANSES, France), exploring the health effects of the Mediterranean diet, recently published an important comment in the British Medical Journal that should be embraced by committees formulating drinking guidelines (8): “The new drinking guidelines do not adequately account for the complex interactions of alcohol with other factors in the diet (1). For example, low to moderate alcohol consumption during a meal…
The present study provides important data supporting that light-to-moderate consumption of alcoholic beverages has favorable effects on most blood lipid levels. Health benefits of low-to-moderate consumption of alcoholic beverages are well documented. However, the mechanisms involved are not entirely clear. Several controlled studies have suggested that the protective effect might be mitigated through an improved blood lipid profile. Thus, a group of US researchers used an innovative approach - the Mendelian Randomization (MR) (*) - to help determine the degree…

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