Osteoporosis

 

Osteoporosis is a disease characterized by low bone mass and deterioration of bone tissue. This leads to increased bone fragility and risk of fracture (broken bones), particularly of the hip, spine, wrist and shoulder. It frequently goes undiagnosed until a fracture occurs, as there are no warning signs or symptoms, and adds to the burden of high health care costs.

Drinking a moderate amount of alcoholic beverages as part of a healthy lifestyle may benefit women’s bone health, lowering their risk of developing osteoporosis. Bones are in a constant state of remodelling with old bone being removed and replaced with new bone tissue. In individuals with osteoporosis, more bone is lost than reformed resulting in porous, weak bones. About 80% of all individuals with osteoporosis are women, and postmenopausal women face an even greater risk because estrogen, a hormone that helps to keep bone remodelling in balance, decreases after menopause. Several studies have shown that moderate drinkers have a higher bone density than non-drinkers or heavy drinkers, but these studies have provided no explanation for the differences in bone density. Researchers reported that the consumption of alcoholic beverages may raise estrogen synthesis or may behave similarly to estrogen by reducing bone turnover, but exactly how alcoholic beverages can reduce the risk of osteoporosis has not yet been clearly established.

 

The above summary provides an overview of the topic, for more details and specific questions, please refer to the articles in the database.

 

OBJECTIVE: Epidemiological studies indicate that higher bone mass is associated with moderate alcohol consumption in postmenopausal women. However, the underlying cellular mechanisms responsible for the putative beneficial effects of alcohol on bone are unknown. Excessive bone turnover, combined with an imbalance whereby bone resorption exceeds bone formation, is the principal cause of postmenopausal bone loss. This study investigated the hypothesis that moderate alcohol intake attenuates bone turnover after menopause. METHODS: Bone mineral density was determined by dual-energy x-ray absorptiometry in 40 healthy postmenopausal women (mean +/- SE age, 56.3 +/- 0.5 y) who consumed alcohol at 19 +/- 1 g/day. Serum levels of the bone formation marker osteocalcin and the resorption marker C-terminal telopeptide (CTx) were measured by immunoassay at…
Alcohol is widely consumed across the world. It is consumed in both social and cultural settings. Until recently, two types of alcohol consumption were recognized: heavy chronic alcohol consumption or light consumption. Today, there is a new pattern of consumption among teenagers and young adults namely: binge drinking. Heavy alcohol consumption is detrimental to many organs and tissues, including bones, and is known to induce secondary osteoporosis. Some studies, however, have reported benefits from light alcohol consumption on bone parameters. To date, little is known regarding the effects of binge drinking on bone health. Here, we review the effects of three different means of alcohol consumption: light, heavy, and binge drinking. We also review the detailed literature on the different…
BACKGROUND: Moderate alcohol consumption has been shown to be positively associated with increased bone mineral density (BMD). However, other lifestyle choices have also been shown to have an effect on bone health. OBJECTIVE: The objective was to examine the association between alcohol intake and BMD in women around menopause in the United Kingdom and to determine whether any association is independent of other lifestyle choices. DESIGN: A cross-sectional study design was used to examine the relation between alcohol intake and BMD in a cohort of 3218 women aged 50-62 y from the Aberdeen Prospective Osteoporosis Screening Study. Women were grouped into clusters according to their lifestyle choices. ANCOVA was used to examine the effect of categorized alcohol intake on BMD…
OBJECTIVE: Findings regarding alcohol consumption and bone mineral density (BMD) in elderly women have been inconsistent. The objective of the present study was to explore the association of alcohol intake with BMD in elderly women. DESIGN: This cohort study included women from the population-based Kuopio Osteoporosis Risk Factor and Prevention - Fracture Prevention Study (OSTPRE-FPS). Alcohol intake and potential confounders were assessed at baseline and after 3 years of follow-up using a lifestyle questionnaire. In addition, an FFQ was distributed in the third year to measure dietary intake, including alcohol. Women underwent BMD measurements at the femoral neck and lumbar spine at baseline and after 3 years of follow-up. SETTING: Kuopio Province, Finland. SUBJECTS: Three hundred elderly women (mean age…
BACKGROUND: Moderate intake of alcohol has been reported to have beneficial effects on bone. However, different classes of alcoholic beverages have not been investigated. OBJECTIVE: Our aim was to determine the association between intake of total alcohol or individual alcoholic beverages and bone mineral density (BMD). DESIGN: Adjusting for potential confounding factors, we examined alcohol intakes and BMD at 3 hip sites and the lumbar spine in 1182 men and in 1289 postmenopausal and 248 premenopausal women in the population-based Framingham Offspring cohort (age: 29-86 y). RESULTS: Men were predominantly beer drinkers, and women were predominantly wine drinkers. Compared with nondrinkers, hip BMD was greater (3.4-4.5%) in men consuming 1-2 drinks/d of total alcohol or beer, whereas hip and spine…
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The authors have taken reasonable care in ensuring the accuracy of the information herein at the time of publication and are not responsible for any errors or omissions. Read more on our disclaimer.